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Meet the 2025 $200K Challenge Finalists

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Butterfly Biosciences, Inc. 

Visualization platform that integrates real-time imaging, automated fluid management, and AI-driven diagnostics to provide a faster, more accurate, and less invasive alternative to existing gynecologic procedures.

 
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Cellorama

Revolutionizing 3D cell analysis during preclinical studies with its innovative patent-pending technologies. Providing a streamlined, all-in-one solutions that enables 3D cell analysis, improving results and minimizing waste.

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CranioSense

IPASS, a portable, noninvasive device for monitoring intracranial pressure. Unlike other methods, it eliminates inter-operator variability and the need for specialized training, making it as easy to use as a pulse oximeter.

 
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Detectpath (UML)

SurgiSense is an advanced, radiation-free surgical sensor system for precision spinal
guidance. Seamlessly integrating with minimally invasive tools, it will enhance accuracy in
pedicle screw placement, reduce complications, and improve workflow efficiency.

 
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Elastro

A FlexMind system combines minimally-invasive, flexible, electronic neural implants with a skull mounted CPU to enable breakthrough treatments for epilepsy and other diseases.

 
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Fideliomed

A digital diagnostic platform for real-time detection of common and treatable diseases in primary care, initially focusing on anemia.

 
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Lia Eyecare

A pioneering ophthalmology startup revolutionizing the treatment of Dry Eye Disease (DED) through a neurological approach to natural tear stimulation.

 
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Limax Biosciences

HemoMax™ is a next-generation, fully degradable hydrogel-based hemostatic agent
designed for provide rapid, effective bleeding control in surgical and trauma settings.

 
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Lucie Medical

The Kira Device actively drains blood and fluid from the uterine cavity into a standard suction canister immediately after placenta delivery, allowing the surgical team to assess blood loss in real-time during and after the postpartum period.

 
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Materialize Bio

Novel, scalable 3D manufacturing method that preserves the regenerative, antimicrobial, and biodegradable properties of natural biopolymers.

 
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RT MicroDX

RT MicroDx is redefining home and point-of-care diagnostics by offering a fully sustainable,
accessible, and highly sensitive alternative to PCR testing.

 
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Sequest Bio

A next-generation AI platform to predict breast cancer metastasis and residual disease (RD), addressing the critical need for more accurate recurrence risk assessment.

 
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Sports Impact Technologies

A compact, behind-the-ear wearable that detects head impacts in real time. Using proprietary sensor technology, it records linear and angular accelerations, transmitting data instantly to coaches, medical staff, or safety officials for immediate decision-making, reducing recovery times, and ensuring no concussion goes undetected.

 
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University of Massachusetts Lowell

A urinary test for muscle health using a biomarker linked to muscle damage, designed to adapt an existing ELISA assay into a point-of-care device for easy use by untrained individuals.

 
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WiseAI

 AI copilot for senior care facilities to deliver proactive care, reduce hospitalizations, and improve profitability.