Applications for the 14th annual $200K Challenge are now closed.
The University of Massachusetts’ Medical Device Development Center (M2D2) is pleased to host the 14th Annual M2D2 $200K Challenge, an opportunity designed to showcase the innovative ideas and entrepreneurial spirit of seed and early-stage medical device and biotech companies.
While applications are now closed, don’t miss your chance to be part of the action! Join us on March 26th at the UML iHub to witness the exciting pitches, connect with top industry leaders, investors, and innovators, and discover the next wave of breakthroughs in life sciences.
Be there to see who takes home a share of the $200K in in-kind resources and cash prizes—and make valuable connections that could help propel your startup forward!
About the $200K Challenge
The $200K Challenge is an annual start-up competition hosted by M2D2, focused on identifying and rewarding disruptive companies in the medical technology and biotechnology industries.
Every year we receive scores of entries from entrepreneurs worldwide. This year, 15 finalists will become eligible to win a share of our $200,000 purse of sponsor-provided, in-kind services and $100,000 in cash awards . These services include lab and office space; engineering, product development, legal, regulatory, clinical, and business services. Past winners have been empowered to bring their innovations to life—and to market.
We welcome innovations that address the full range of medical device challenges, and this year we're especially interested in ideas that fall under our four unique innovation tracks.
Watch the 2025 $200K Challenge Info Session
Hear M2D2 team members and a previous Challenge as they discuss:
- The application process
- How to impress the judges
- The lasting impact felt by $200K Challenge finalists
Learn more about the 2025 areas of interest!
MARK YOUR CALENDAR!
Jan. 8 — Applications Open
January 15 — Virtual Info Session: "All About the Challenge"
Feb. 16 — Application Deadline
March 10 — Finalists Announced
March 10 - March 25 — Coaching Sessions for Finalists
March 26 — Finalist Pitch-Off and Award Announcement in Lowell

Looking back at the 2024 $200K Challenge
On March 27th, the 2024 finalists came to compete for a chance to win thousands to advance their novel healthcare solution.
We had a record number of attendees in 2024, with a sold out crowd to watch our 15 start-ups present.

First Place Winner: Relavo Medical

Second Place Winner: EndoShunt Medical

Third Place Winner: Neuraura
Thank you to our Corporate Partners
Massachusetts Life Sciences Center • Withum • UMass Chan Medical School • RQMIS
Hologic • UMass CAPCaT • Sallop • MPR • Mintz
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