The 14th annual $200K Challenge is open!

The University of Massachusetts’ Medical Device Development Center (M2D2) is pleased to host the 14th Annual M2D2 $200K Challenge, an opportunity designed to showcase the innovative ideas and entrepreneurial spirit of seed and early-stage medical device and biotech companies.

Applications are officially open for the 2025 $200K Challenge! Get your application started today.

About the Challenge


The $200K Challenge is an annual start-up competition hosted by M2D2, focused on identifying and rewarding disruptive companies in the medical technology and biotechnology industries.

Every year we receive scores of entries from entrepreneurs worldwide. This year, 15 finalists will become eligible to win a share of our $200,000 purse of sponsor-provided, in-kind services and $75,000 in cash awards . These services include lab and office space; engineering, product development, legal, regulatory, clinical, and business services. Past winners have been empowered to bring their innovations to life—and to market.  

We welcome innovations that address the full range of medical device challenges, and this year we're especially interested in ideas that can benefit from our association with the U.S. government's BARDA DRIVe initiative.

On March 26th, 15 finalists will pitch their solutions to a panel of experts and compete for a share of $200,000 in in-kind awards.

We had a record number of attendees in 2024, with a sold out crowd to watch our 15 start-ups present.

First Place Winner: Relavo Medical
Second Place Winner: EndoShunt Medical
Third Place Winner: Neuraura

2025 $200K Challenge Info Session

Learn about the 2025 $200K Challenge, including this year's new areas of interest, the application process, and how you can submit an application that stands out.

REGISTER TODAY

MARK YOUR CALENDAR!

Key 2025 Challenge Dates

Jan. 8 — Applications Open
January 15 — Virtual Info Session: "All About the Challenge"
Feb. 16 — Application Deadline
March 1 — Finalists Announced
March 3 - March 25 — Coaching Sessions for Finalist

March 26 — Finalist Pitch-Off and Award Announcement in Lowell 

2022 $200K Challenge Highlights

Thank you to our Corporate Partners

Massachusetts Life Sciences Center • Withum • UMass Chan Medical School • RQMIS
Hologic • UMass CAPCaT • Sallop • MPR • Mintz •

Latins In Bio  • VETSRISE  • Asians In Biotech