Get Ready for the 15th Annual $200K Challenge!
About the $200K Challenge
The $200K Challenge is an annual start-up competition hosted by M2D2, focused on identifying and rewarding disruptive companies in the medical technology and biotechnology industries.
Every year we receive scores of entries from entrepreneurs worldwide. This year, 15 finalists will become eligible to win a share of our $200,000 purse of sponsor-provided, in-kind services and $100,000 in cash awards . These services include lab and office space; engineering, product development, legal, regulatory, clinical, and business services. Past winners have been empowered to bring their innovations to life—and to market.
We welcome innovations that address the full range of medical device challenges, and this year we're especially interested in ideas that fall under our four unique innovation tracks.
Watch the 2025 $200K Challenge Info Session
Hear M2D2 team members and a previous Challenge as they discuss:
- The application process
- How to impress the judges
- The lasting impact felt by $200K Challenge finalists
MARK YOUR CALENDAR!
January 5th — Applications Open
January 15 — Virtual Info Session: "All About the Challenge"
February 15th — Application Deadline
March 9th — Finalists Announced
March 10th - March 24th — Coaching Sessions for Finalists
March 25th — Finalist Pitch-Off and Award Announcement in Lowell

Looking back at the 2025 $200K Challenge
On March 26th, the 2025 finalists came to compete for a chance to win thousands to advance their novel healthcare solution.
We had a standout crowd to watch our 15 start-ups present.

First Place Winner: CranioSense

Second Place Winner: Limax Biosciences

Third Place Winner: Sports Impact Technologies
Thank you to our Corporate Partners
Massachusetts Life Sciences Center • Withum • UMass Chan Medical School • RQMIS
Hologic • UMass CAPCaT • Sallop • MPR • Mintz
Latins In Bio • VETSRISE • Asians In Biotech • bene : studio